Femoral Nailing-related Coagulopathy Determined by First-hit Magnitude

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Stimulation of the inflammatory system by reamed and unreamed nailing of femoral fractures. An analysis of the second hit.

It has been suggested that reamed intramedullary nailing of the femur should be avoided in some patients with multiple injuries. We have studied prospectively the effect of femoral reaming on the inflammatory process as implicated in the pathogenesis of acute respiratory distress syndrome (ARDS) and multiple-organ failure (MOF). We studied changes in the levels of serum interleukin-6 (IL-6) (pr...

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ژورنال

عنوان ژورنال: Clinical Orthopaedics & Related Research

سال: 2008

ISSN: 0009-921X

DOI: 10.1007/s11999-007-0066-6